Mykonos is the most cosmopolitan island in Greece, and arriving by yacht changes your relationship with it entirely. You anchor off the old town in the morning before the day boats arrive, visit the sacred ancient site of Delos on your own schedule, and find the secluded swimming bays that the ferry passengers never reach.
As part of a Cyclades charter itinerary, Mykonos is typically a two-night stop, one night at anchor off the old town, one in a marina or at the northern coast anchorages. Paros, Naxos and Delos are all within a few hours' sail. The Meltemi winds in July and August make for fast, exhilarating sailing on this part of the Cyclades.
Vlamis Yachts departs from Alimos Marina in Athens. Mykonos is a full day's sail or an overnight passage, most charterers include it as part of a one-week Cyclades itinerary covering 4 to 6 islands.